Colladerma is a fully comprehensive concept in beauty
The researchers team of Colladerma Laboratories from Sanimed Advanced Biotechnology Research Institute, create unique and safe formulations based on a unique concept that the products contain marine collagen, hyaluronic acid but also functional and biocompatible actives, of last generation.
AC Marine Collagen PF
The aging process of the skin makes its presence felt in the dermis. It is manifested by altering the collagen fibers. To delay such destruction process, our products include bio-peptides obtained by the hydrolysis of collagen extracted from marine organisms. These bio-peptides has been optimized through the modern biotechnology processes that have documented clinical studies as a basis.
X50 HyaluFiller - The Cosmetic Drone™
X50 HyaluFiller – The Cosmetic DroneTM is the first cosmetic drone, an cosmetic alternative of the products from the Dermalfillers class, which include the classic but current injectable hyaluronic acid. The Cosmetic DroneTM induces a complementary mechanism to stimulate in situ the biosynthesis of hyaluronic acid, being a new transport system, delivery and controlled release of the active ingredients for cosmetics and cosmeceutics, based on micro- and nano-capsules that can take quite specific quantities of molecules. Due the ligands on their surface, the carrying particles can be selectively retained by the target cells that internalize them, together with the content that they carry. For cosmetic purposes, the particles from X50 HyaluFiller are “loaded” with dodecapeptides which stimulates the dermal fibroblasts in order to biosynthesis the collagen, but also the elastin and hyaluronic acid. The effects of using this drone installs quickly and provide the cosmetic skin rejuvenation.
Lipo® Hyaluronic Acid
The hyaluronic acid and its derivatives are ubiquitous natural components in the soft and wet tissues of the human body, ensuring their fluid balance. Like the other representatives of the class of glycosaminoglycans, the hyaluronic acid is able to retain large quantities of water, contributing to a specific series of dermis processes: the hydric homeostasis, the tissue repair and the immune shield. Applied on the skin, the sodium salt of the hyaluronic acid ensures its flexibility, integrity and the hydration of lower cell layers, maintaining the skin healthy.
The Skin Maker™
The product is actually the second cosmetic drone with immediate effects and role in restoring the skin’s ability to act as a selective barrier. This drone operates through three complementary mechanisms: reconstructing tissues in the dermis, maintaining the structural integrity of the morphological entities of skin and the additional hydrating of basal layer of the epidermis, the only layer of cells capable of dividing and to regenerate the entire epidermis. The molecules which SkinMakerTM is able to transport and deliver are proteins with key roles in regulating the biosynthesis of epidermal keratins, at tissular level, respectively the filaggrine and loricrine.
Innovative active with a strong lifting effect and smoothing of the skin. In fact, this product generates a three-dimensional matrix consisting of oligosaccharides extracted from the root of Cichorium intybus, which provides the progressive release of its active principles. These active ingredients are transferred through the epidermis into the dermis, where they are gradually released, acting on living cells, changing their behavior and their abilities to make the abundant biosynthesis of the young skin specific components.
This active is a mixture of two natural components: a pentasaccharide extracted from marine Enteromorpha compressa and a galactomanan obtained from the countryside (Caesalpinia spinosa). Their combined action restores and maintains the homeostasis of the extracellular matrix of the dermis.
It is an adjunct with the role of “tunneling” and sequential delivery of small molecule bioactive compounds, which it guides in their transfer through the epidermis. It also transfers abundantly water molecules, ensuring a rapid, uniform and durable rehydration of the dermis, especially its junction with the epidermis.
It is a mixture of highly protective polyphenols against ultraviolet radiation, extracted from stem cells cultured in the laboratory after being taken from the red cowberry (Vaccinium vitis-idaea). The extract also contains vitamins C and E, active in the recovery of sun-damaged skin through its infrared components.
This product in addition to ultraviolet protection, reduces and regulates sebum secretion, the latter being the active collector of pollutant powders and the mediator of their penetration into the skin. As a result, natural color and luminosity of the skin are restored.
The active is an extract of sesame seeds (Sesamum indicum), rich in sesamine, a lignan with direct effect on subcutaneous fat tissues. Additionally, the extract components restore the epidermis suppleness and firmness. In vivo studies quantified this effect by measuring the transpidermale water loss and of the cutaneous micro-relief. The active principles of the extract increases the lipids accumulation in the adipose tissues, filling the subcutaneous depleted reserves and helping in reduce the unwanted wrinkles and skin folds.
It is a synergistic blend of metabolites extracted from Enteromorpha compressa, from indian basil (Ocimum tenuiflorum) and armor (Silybum marianum). It is rich in ursolic acid and silymarin, inhibiting prostaglandin synthesis involved in inflammatory mechanisms in the epidermis and protecting the membrane of living cells from irritating mechanical factors (such as improper use of scrub products). The ultimate effect is to soften and combat local inflammation.
It is an extract obtained by enzymatic hydrolysis of the chinese pulp Poria cocos (also known in latin Wolfiporia extensa), which contains well-determined amounts of pachyman, a biologically active polysaccharide. The benefits of using this extract are known in traditional chinese medicine and are scientifically substantiated by confirming the direct beneficial effects on the biosynthesis of collagen and hyaluronic acid in the dermis and the stimulating role on local microcirculation.
It is an energetically active extract in epidermis and dermis regeneration, obtained through biotechnology from of Citrus sinensis stem cells. Produced by Provital Group, Citrustem ™ is the favorite of elite cosmetologists. It includes vegetable primary and secondary metabolites, with highly effective in controlling tissue regeneration. The amino acids, polypeptides and organic acids it contains play a major role in the tissue remodeling of mature skin. The effects of the product have been demonstrated by in vivo studies by specific biomechanical measurements.
It is a combination of two natural extracts from the marlin root (Rhaponticum carthamoides) and the Zizyphus spinosa seeds, a plant heavily used in traditional chinese medicine. The first one is rich in phytoecdysteroid and the other in triterpenic acids. The synergistic action of the two extracts leads to stimulation of the synthesis and of the essential components for the extracellular matrix functionality of the dermis as well as the interface between the dermis and the epidermis, namely collagen IV, laminin, collagen VII and desmoplain.
It is an extract of the medicinal plant “wolf mouth” (Scutellaria baicalensis), which contains baicaline, a glucuronic derivative of the flavonoid family – baicaleine, which inhibits senescence in epidermal cells. Studies to demonstrate product efficacy quantify its effects by highlighting epidermal microarhitecture, a critical parameter in assessing cellular aging process.
It is an extract from “St. John’s grass” (Salvia sclarea) which induces an intense moisturizing effect. The extract contains a balanced mixture of triterpenic acids, flavonoids and volatile oils.
Our products include a first product designed to effectively remove the non-viable skin layer of the epidermis. In this sense, CelluloscrubTM is a new generation of modified cellulose derivative, of last generations, that provides the gentle mechanical exfoliation of the superficial and labile skin layer. This derivative is intrinsically eco-friendly, being of natural origin but also fully biodegradable.
Exfoliating action is synergistically completed by Diatomite™, a microscopic silica powder, abrasive moderately, with controlled three-dimensional granulation and morphology.
ABS Pap-Ango Enzyme PF®
Mechanical exfoliation is enhanced by the action of some proteolytic enzymes offered by natural extracts of Carica papaya, Mangifera indica, Raphanus sativus. The enzyme complex and accompanying excipients provide antibacterial and skin-smoothing effects.
Effective removal of exfoliated components from the skin is facilitated by this biodegradable natural surfactant, of new generation, that does not irritate the skin.
Throughout and at the end of preliminary skin cleansing, Caresoft reduces discomfort, adjusts the pH of the epidermis and restores its barrier functions, improving the integrity of its substrates.
Floral waters, naural butters and precious ecocertified organic oils
They are selected and homogenized to optimize the release of active ingredients and to enhance the soothing effect. Among the organic oils that we have included in Colladerma collection are: primerose oil, rice oil, sesame oil, sweet almond oil.
Vitamins A, C and E, along with omega-6 linoleic acid, also known as vitamin F
These elements are essential in revitalizing of epidermal functions, especially for controlling cell proliferation in the basal layer and for enhancing epidermis adhesion to the dermis.